Anti-EPHB4 Polyclonal Antibody
品牌:solarbio | 货号:K003647P
| 英文名称 | Anti-EPHB4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HFASD;HTK;MYK1;TYRO11 |
| 应用 | WB |
| 稀释比例 | WB 1:200-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 108kDa |
| Gene ID | 2050 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EPHB4 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EPHB4 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | P54760 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |