Anti-RHOB Polyclonal Antibody
品牌：solarbio | 货号：K007376P
| 英文名称 | Anti-RHOB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARH6;ARHB;RHOH6 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 22kDa |
| Gene ID | 388 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human RHOB |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human RHOB |
| Subcellular Locations | Cell membrane Endosome Membrane Nucleus |
| Swiss Prot | P62745 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |