Anti-SAV1 Polyclonal Antibody
品牌：solarbio | 货号：K006142P
| 英文名称 | Anti-SAV1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SAV;WW45;WWP4 |
| 应用 | WB |
| 稀释比例 | WB 1:1000-4000. |
| 交叉反应 | Human |
| 蛋白分子量 | 45kDa |
| Gene ID | 60485 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SAV1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SAV1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9H4B6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. |