Anti-CYFIP1 Polyclonal Antibody
品牌：solarbio | 货号：K006303P
| 英文名称 | Anti-CYFIP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | P140SRA-1;SHYC;SRA-1;SRA1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:1000-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 145kDa |
| Gene ID | 23191 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CYFIP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CYFIP1 |
| Subcellular Locations | Cell junction Cell projection Cytoplasm lamellipodium perinuclear region ruffle synapse synaptosome |
| Swiss Prot | Q7L576 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | CYFIP1 are cytoplasmic proteins belonging to the CYFIP family. Both proteins bind GTP-bound Rac 1 to release FRM1 in its active state, which is thought to regulate mRNA translation of neural cytoskeletal proteins. A loss of CYFIP1 and CYFIP2 leads to mutant neurons with defective axonal growth and motor function. Also designated specifically Rac1-associated protein 1 (sra-1) or p140sra-1, CYFIP1 contains 1,253 amino acids and is a component of the WAVE2 complex. |