Anti-ANPEP Polyclonal Antibody
品牌：solarbio | 货号：K007597P
| 英文名称 | Anti-ANPEP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APN;CD13;LAP1;P150;PEPN;GP150 |
| 应用 | IHC |
| 稀释比例 | IHC 1:100-300. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 110kDa |
| Gene ID | 290 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ANPEP |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ANPEP |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P15144 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. |