Anti-PAK4 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PAK4 Polyclonal Antibody

品牌:solarbio | 货号:K008214P

英文名称 Anti-PAK4 Polyclonal Antibody
宿主 Rabbit
别名 KIAA1142;Serine/threonine-protein kinase PAK 4
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 64kDa
Gene ID 10298
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PAK4
性状 液体
Public Immunogen Range Recombinant protein of human PAK4
Subcellular Locations Cytoplasm
Swiss Prot O96013
克隆类型 Polyclonal Antibody
背景资料 PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.