Anti-L1CAM Polyclonal Antibody
品牌：solarbio | 货号：K005910P
| 英文名称 | Anti-L1CAM Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CAML1;CD171;HSAS;HSAS1;MASA;MIC5;N-CAM-L1;N-CAML1;NCAM-L1;S10;SPG1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 140kDa |
| Gene ID | 3897 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human L1CAM |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human L1CAM |
| Subcellular Locations | Cell membrane Cell projection Single-pass type I membrane protein growth cone |
| Swiss Prot | P32004 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. |