Anti-ANP32E Polyclonal Antibody
品牌：solarbio | 货号：K007756P
| 英文名称 | Anti-ANP32E Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LANPL;LANP-L |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 31kDa |
| Gene ID | 81611 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ANP32E |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ANP32E |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9BTT0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The Anp32 family consists of 32 evolutionarily-conserved proteins and is included within the superfamily of leucine-rich repeat (LRR) proteins. Leucine-rich acidic nuclear protein-like (LANPL), also called ANP32E or Cpd1, is a member of the Anp32 family. LANPL is located in the cytoplasm of peripheral blood leukocytes, colon, small intestine, prostate, thymus, spleen, skeletal muscle, liver and kidney. It has also been detected in the nucleus, cytoplasm and membrane of multiple brain regions. Upon phosphorylation, LANPL colocalizes and inhibits protein phosphatase 2A (PP2A), but does not inhibit PP1. LANPL modulates cell signalling and transduction of gene expression to regulate the morphology and dynamics of the cytoskeleton, cell adhesion, neural development and cerebellar morphogenesis. |