Anti-PDCD1 Polyclonal Antibody
品牌:solarbio | 货号:K007618P
英文名称 |
Anti-PDCD1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
PD1;PD-1;CD279;SLEB2;hPD-1;hPD-l |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
32kDa |
Gene ID |
5133 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human PDCD1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human PDCD1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q15116 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |