Anti-FMR1 Polyclonal Antibody
品牌:solarbio | 货号:K004105P
英文名称 |
Anti-FMR1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
FMRP;FRAXA;POF;POF1 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
71kDa |
Gene ID |
2332 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human FMR1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human FMR1 |
Subcellular Locations |
Cytoplasm Nucleus nucleolus |
Swiss Prot |
Q06787 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |