Anti-TRAF3IP2 Polyclonal Antibody
品牌:solarbio | 货号:K004788P
英文名称 |
Anti-TRAF3IP2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ACT1;C6orf2;C6orf4;C6orf5;C6orf6;CANDF8;CIKS;PSORS13 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
65kDa |
Gene ID |
10758 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TRAF3IP2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TRAF3IP2 |
Subcellular Locations |
Cytosol Nucleus |
Swiss Prot |
O43734 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. |