Anti-ASIP Polyclonal Antibody
品牌：solarbio | 货号：K004831P
| 英文名称 | Anti-ASIP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AGSW;AGTI;AGTIL;ASP;SHEP9 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 15kDa |
| Gene ID | 434 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ASIP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ASIP |
| Subcellular Locations | Secreted |
| Swiss Prot | P42127 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. |