Anti-NCOR1 Polyclonal Antibody
品牌:solarbio | 货号:K004966P
| 英文名称 | Anti-NCOR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | N-CoR;N-CoR1;PPP1R109;TRAC1;hN-CoR |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 270kDa |
| Gene ID | 9611 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NCOR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NCOR1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | O75376 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. |