Anti-CTSC Polyclonal Antibody
品牌：solarbio | 货号：K005811P
| 英文名称 | Anti-CTSC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CPPI;DPP-I;DPP1;DPPI;HMS;JP;JPD;PALS;PDON1;PLS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 1075 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CTSC |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CTSC |
| Subcellular Locations | Lysosome |
| Swiss Prot | P53634 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. |