Anti-FMR1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-FMR1 Polyclonal Antibody

品牌:solarbio | 货号:K004329P

英文名称 Anti-FMR1 Polyclonal Antibody
宿主 Rabbit
别名 FMRP;FRAXA;POF;POF1
应用 WB
稀释比例 WB 1:500-1000.
交叉反应 Human Rat
蛋白分子量 71kDa
Gene ID 2332
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human FMR1
性状 液体
Public Immunogen Range A synthetic peptide of human FMR1
Subcellular Locations Cytoplasm Nucleus nucleolus
Swiss Prot Q06787
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5′ UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.