Anti-CD33 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD33 Polyclonal Antibody

品牌:solarbio | 货号:K006979P

英文名称 Anti-CD33 Polyclonal Antibody
宿主 Rabbit
别名 p67;SIGLEC3;SIGLEC-3
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 40kDa
Gene ID 945
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CD33
性状 液体
Public Immunogen Range Recombinant protein of human CD33
Subcellular Locations Cytoplasm
Swiss Prot P20138
克隆类型 Polyclonal Antibody
背景资料 CD33?or Siglec-3 is a?transmembrane receptor?expressed on cells of?myeloid?lineage.?It is usually considered myeloid-specific, but it can also be found on some?lymphoid?cells. Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.