Anti-EPS15L1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-EPS15L1 Polyclonal Antibody

品牌:solarbio | 货号:K006919P

英文名称 Anti-EPS15L1 Polyclonal Antibody
宿主 Rabbit
别名 EPS15R
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse
蛋白分子量 94kDa
Gene ID 58513
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human EPS15L1
性状 液体
Public Immunogen Range Recombinant protein of human EPS15L1
Subcellular Locations Cytoplasm
Swiss Prot Q9UBC2
克隆类型 Polyclonal Antibody
背景资料 Epidermal growth factor receptor substrate 15-like 1?is a?protein?that in humans is encoded by the?EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.