Anti-EPS15L1 Polyclonal Antibody
品牌:solarbio | 货号:K006919P
| 英文名称 | Anti-EPS15L1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EPS15R |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:25-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 94kDa |
| Gene ID | 58513 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human EPS15L1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human EPS15L1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9UBC2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Epidermal growth factor receptor substrate 15-like 1?is a?protein?that in humans is encoded by the?EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. |