Anti-EPS15L1 Polyclonal Antibody
品牌:solarbio | 货号:K006919P
英文名称 |
Anti-EPS15L1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EPS15R |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
94kDa |
Gene ID |
58513 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human EPS15L1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human EPS15L1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q9UBC2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Epidermal growth factor receptor substrate 15-like 1?is a?protein?that in humans is encoded by the?EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. |