Anti-PDCD10 Polyclonal Antibody
品牌：solarbio | 货号：K006814P
| 英文名称 | Anti-PDCD10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CCM3;TFAR15 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 25kDa |
| Gene ID | 11235 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PDCD10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PDCD10 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q9BUL8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. |