Anti-OAS2 Polyclonal Antibody
品牌:solarbio | 货号:K006804P
英文名称 |
Anti-OAS2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
p69 OAS / p71 OAS;2-5A synthase 2 |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
82kDa |
Gene ID |
4939 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human OAS2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human OAS2 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P29728 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. |