Anti-TNFRSF11B Polyclonal Antibody
品牌:solarbio | 货号:K006807P
英文名称 |
Anti-TNFRSF11B Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
OPG;TR1;OCIF |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
46kDa |
Gene ID |
4982 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human TNFRSF11B |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human TNFRSF11B |
Subcellular Locations |
cytoplasm Nucleus |
Swiss Prot |
O00300 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.? |