Anti-TNFRSF11B Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-TNFRSF11B Polyclonal Antibody

品牌:solarbio | 货号:K006807P

英文名称 Anti-TNFRSF11B Polyclonal Antibody
宿主 Rabbit
别名 OPG;TR1;OCIF
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:25-100.
交叉反应 Human Mouse Rat
蛋白分子量 46kDa
Gene ID 4982
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TNFRSF11B
性状 液体
Public Immunogen Range Recombinant protein of human TNFRSF11B
Subcellular Locations cytoplasm Nucleus
Swiss Prot O00300
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.?