Anti-CDK9 Polyclonal Antibody
品牌:solarbio | 货号:K006698P
英文名称 |
Anti-CDK9 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
TAK;C-2k;CTK1;CDC2L4;PITALRE |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
43kDa |
Gene ID |
1025 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human CDK9 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human CDK9 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
P50750 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. |