Anti-CDK9 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CDK9 Polyclonal Antibody

品牌:solarbio | 货号:K006698P

英文名称 Anti-CDK9 Polyclonal Antibody
宿主 Rabbit
别名 TAK;C-2k;CTK1;CDC2L4;PITALRE
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 43kDa
Gene ID 1025
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CDK9
性状 液体
Public Immunogen Range Recombinant protein of human CDK9
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P50750
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.