Anti-MARK1 Polyclonal Antibody
品牌：solarbio | 货号：K007764P
| 英文名称 | Anti-MARK1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MARK;Par1c;Par-1c |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 89kDa |
| Gene ID | 4139 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MARK1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MARK1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9P0L2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | MARK1 is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart. |