Anti-AKR1C4 Polyclonal Antibody
品牌:solarbio | 货号:K005241P
英文名称 |
Anti-AKR1C4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
3-alpha-HSD;C11;CDR;CHDR;DD-4;DD4;HAKRA |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
37kDa |
Gene ID |
1109 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human AKR1C4 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human AKR1C4 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P17516 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |