Anti-TNFRSF4 Polyclonal Antibody
品牌:solarbio | 货号:K007872P
英文名称 |
Anti-TNFRSF4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
OX40;ACT35;CD134;IMD16;TXGP1L |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human |
蛋白分子量 |
29kDa |
Gene ID |
7293 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TNFRSF4 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TNFRSF4 |
Swiss Prot |
P43489 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.? |