Anti-CYB5R3 Polyclonal Antibody
品牌：solarbio | 货号：K007930P
| 英文名称 | Anti-CYB5R3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | B5R;DIA1 |
| 应用 | IHC |
| 稀释比例 | IHC 1:30-150. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 34/38kDa |
| Gene ID | 1727 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CYB5R3 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CYB5R3 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P00387 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. |