Anti-CD8A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CD8A Polyclonal Antibody

品牌:solarbio | 货号:K007994P

英文名称 Anti-CD8A Polyclonal Antibody
宿主 Rabbit
别名 CD8;MAL;p32;Leu2
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:30-150.
交叉反应 Human
蛋白分子量 26kDa
Gene ID 925
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CD8A
性状 液体
Public Immunogen Range A synthetic peptide of human CD8A
Subcellular Locations Membrane
Swiss Prot P01732
克隆类型 Polyclonal Antibody
背景资料 The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.