Anti-BMP5 Polyclonal Antibody
品牌:solarbio | 货号:K005810P
英文名称 |
Anti-BMP5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BMP5 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
52kDa |
Gene ID |
653 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human BMP5 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human BMP5 |
Subcellular Locations |
Secreted |
Swiss Prot |
P22003 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. |