Anti-PVRL4 Polyclonal Antibody
品牌:solarbio | 货号:K007119P
英文名称 |
Anti-PVRL4 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LNIR;PRR4;EDSS1;nectin-4 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:100-300. |
交叉反应 |
Human Mouse |
蛋白分子量 |
55kDa |
Gene ID |
81607 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PVRL4 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PVRL4 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q96NY8 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |