Anti-CBS Polyclonal Antibody
品牌：solarbio | 货号：K008336P
| 英文名称 | Anti-CBS Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HIP4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 61kDa |
| Gene ID | 875 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CBS |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CBS |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P35520 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. |