Anti-CAPNS1 Polyclonal Antibody
品牌：solarbio | 货号：K004596P
| 英文名称 | Anti-CAPNS1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CALPAIN4;CANP;CANPS;CAPN4;CDPS;CSS1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 28kDa |
| Gene ID | 826 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CAPNS1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CAPNS1 |
| Subcellular Locations | Cell membrane Cytoplasm |
| Swiss Prot | P04632 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. |