Anti-NRG3 Polyclonal Antibody
品牌:solarbio | 货号:K007661P
英文名称 |
Anti-NRG3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HRG3;pro-NRG3 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
78kDa |
Gene ID |
10718 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NRG3 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NRG3 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P56975 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 – members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. |