Anti-NRG3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-NRG3 Polyclonal Antibody

品牌:solarbio | 货号:K007661P

英文名称 Anti-NRG3 Polyclonal Antibody
宿主 Rabbit
别名 HRG3;pro-NRG3
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 78kDa
Gene ID 10718
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human NRG3
性状 液体
Public Immunogen Range A synthetic peptide of human NRG3
Subcellular Locations Cytoplasm
Swiss Prot P56975
克隆类型 Polyclonal Antibody
背景资料 This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 – members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4.