Anti-ILF2 Polyclonal Antibody
品牌：solarbio | 货号：K004279P
| 英文名称 | Anti-ILF2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | NF45;PRO3063 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 43kDa |
| Gene ID | 3608 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ILF2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ILF2 |
| Subcellular Locations | Cytoplasm Nucleus nucleolus |
| Swiss Prot | Q12905 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. |