Anti-CHRNG Polyclonal Antibody
品牌：solarbio | 货号：K005529P
| 英文名称 | Anti-CHRNG Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ACHRG |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 58kDa |
| Gene ID | 1146 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CHRNG |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CHRNG |
| Subcellular Locations | Cell junction Cell membrane Multi-pass membrane protein postsynaptic cell membrane synapse |
| Swiss Prot | P07510 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis. |