Anti-ST14 Polyclonal Antibody
品牌：solarbio | 货号：K004341P
| 英文名称 | Anti-ST14 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | ARCI11;HAI;MT-SP1;MTSP1;PRSS14;SNC19;TADG15;TMPRSS14 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 95kDa |
| Gene ID | 6768 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ST14 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ST14 |
| Subcellular Locations | Membrane Single-pass type II membrane protein |
| Swiss Prot | Q9Y5Y6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. |