Anti-SF3B3 Polyclonal Antibody
品牌：solarbio | 货号：K004347P
| 英文名称 | Anti-SF3B3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RSE1;SAP130;SF3b130;STAF130 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 136kDa |
| Gene ID | 23450 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SF3B3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SF3B3 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15393 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron’s branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. |