Anti-SF1 Polyclonal Antibody
品牌：solarbio | 货号：K004516P
| 英文名称 | Anti-SF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BBP;D11S636;MBBP;ZCCHC25;ZFM1;ZNF162 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 68kDa |
| Gene ID | 7536 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SF1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SF1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q15637 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3′ splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. |