Anti-SF1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-SF1 Polyclonal Antibody

品牌:solarbio | 货号:K004516P

英文名称 Anti-SF1 Polyclonal Antibody
宿主 Rabbit
别名 BBP;D11S636;MBBP;ZCCHC25;ZFM1;ZNF162
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 68kDa
Gene ID 7536
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human SF1
性状 液体
Public Immunogen Range Recombinant protein of human SF1
Subcellular Locations Nucleus
Swiss Prot Q15637
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3′ splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.