Anti-USP5 Polyclonal Antibody
品牌:solarbio | 货号:K003763P
英文名称 |
Anti-USP5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ISOT |
应用 |
WB |
稀释比例 |
WB 1:1000-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
96kDa |
Gene ID |
8078 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human USP5 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human USP5 |
Subcellular Locations |
Cytosol Lysosome |
Swiss Prot |
P45974 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]). |