Anti-DHFR Polyclonal Antibody
品牌:solarbio | 货号:K007462P
英文名称 |
Anti-DHFR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
DYR;DHFRP1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-300. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
21kDa |
Gene ID |
1719 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human DHFR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human DHFR |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P00374 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. |