Anti-ERCC2 Polyclonal Antibody
品牌：solarbio | 货号：K004100P
| 英文名称 | Anti-ERCC2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | COFS2;EM9;TFIIH;TTD;TTD1;XPD |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 87kDa |
| Gene ID | 2068 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ERCC2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ERCC2 |
| Subcellular Locations | Cytoplasm Nucleus cytoskeleton spindle |
| Swiss Prot | P18074 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |