Anti-CD27 Polyclonal Antibody
品牌:solarbio | 货号:K106872P
英文名称 |
Anti-CD27 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
S152;S152. LPFS2;T14;TNFRSF7;Tp55;S152.LPFS2;CD27 antigen |
应用 |
IHC |
稀释比例 |
IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
29kDa |
Gene ID |
939 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human CD27 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human CD27 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P26842 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |