Anti-CADH2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CADH2 Polyclonal Antibody

品牌:solarbio | 货号:K106417P

英文名称 Anti-CADH2 Polyclonal Antibody
宿主 Rabbit
别名 CDH2;Cadherin-2;CDw325;CDHN;NCAD;CD325
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human
蛋白分子量 10kDa
Gene ID 1000
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CADH2
性状 液体
Public Immunogen Range A synthetic peptide of human CADH2
Subcellular Locations Cell membrane
Swiss Prot P19022
克隆类型 Polyclonal Antibody
背景资料 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).