Anti-MSH5 Polyclonal Antibody
品牌:solarbio | 货号:K008192P
英文名称 |
Anti-MSH5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
G7;NG23;MUTSH5 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:25-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
93kDa |
Gene ID |
4439 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MSH5 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MSH5 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O43196 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. |