Anti-TNF polyclonal antibody-一抗-抗体-蛋白与免疫

Anti-TNF polyclonal antibody

品牌:solarbio | 货号:K008062P

英文名称 Anti-TNF polyclonal antibody
宿主 Rabbit
别名 DIF;TNFA;TNFSF2;TNLG1F;TNF-alpha
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-300.
交叉反应 Human Mouse
蛋白分子量 26kDa
Gene ID 7124
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human TNF
性状 液体
Public Immunogen Range A synthetic peptide of human TNF
Subcellular Locations Membrane
Swiss Prot P01375
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.