Anti-TNF polyclonal antibody
品牌:solarbio | 货号:K008062P
英文名称 |
Anti-TNF polyclonal antibody |
宿主 |
Rabbit |
别名 |
DIF;TNFA;TNFSF2;TNLG1F;TNF-alpha |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-300. |
交叉反应 |
Human Mouse |
蛋白分子量 |
26kDa |
Gene ID |
7124 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human TNF |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human TNF |
Subcellular Locations |
Membrane |
Swiss Prot |
P01375 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |