Anti-PLAT Polyclonal Antibody
品牌：solarbio | 货号：K007628P
| 英文名称 | Anti-PLAT Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TPA;T-PA |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 63kDa |
| Gene ID | 5327 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human PLAT |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human PLAT |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P00750 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. |