Anti-NPPB Polyclonal Antibody
品牌:solarbio | 货号:K007390P
英文名称 |
Anti-NPPB Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BNP |
应用 |
IHC |
稀释比例 |
IHC 1:40-150. |
交叉反应 |
Human |
蛋白分子量 |
15kDa |
Gene ID |
4879 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human NPPB |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human NPPB |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P16860 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein’s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. |