Anti-NPPB Polyclonal Antibody
品牌:solarbio | 货号:K007390P
| 英文名称 | Anti-NPPB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BNP |
| 应用 | IHC |
| 稀释比例 | IHC 1:40-150. |
| 交叉反应 | Human |
| 蛋白分子量 | 15kDa |
| Gene ID | 4879 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human NPPB |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human NPPB |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P16860 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein’s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. |