Anti-PLEKHG6 Polyclonal Antibody
品牌：solarbio | 货号：K007110P
| 英文名称 | Anti-PLEKHG6 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MyoGEF |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 89kDa |
| Gene ID | 55200 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PLEKHG6 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PLEKHG6 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q3KR16 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis. |