Anti-PLEKHG6 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PLEKHG6 Polyclonal Antibody

品牌:solarbio | 货号:K007110P

英文名称 Anti-PLEKHG6 Polyclonal Antibody
宿主 Rabbit
别名 MyoGEF
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:100-300.
交叉反应 Human Mouse
蛋白分子量 89kDa
Gene ID 55200
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PLEKHG6
性状 液体
Public Immunogen Range Recombinant protein of human PLEKHG6
Subcellular Locations Cytoplasm
Swiss Prot Q3KR16
克隆类型 Polyclonal Antibody
背景资料 PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.