Anti-ITGB5 Polyclonal Antibody
品牌:solarbio | 货号:K006328P
英文名称 |
Anti-ITGB5 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ITGB5 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
88kDa |
Gene ID |
3693 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ITGB5 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ITGB5 |
Subcellular Locations |
Membrane Single-pass type I membrane protein |
Swiss Prot |
P18084 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. |