Anti-ITGB5 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ITGB5 Polyclonal Antibody

品牌:solarbio | 货号:K006328P

英文名称 Anti-ITGB5 Polyclonal Antibody
宿主 Rabbit
别名 ITGB5
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse Rat
蛋白分子量 88kDa
Gene ID 3693
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ITGB5
性状 液体
Public Immunogen Range Recombinant protein of human ITGB5
Subcellular Locations Membrane Single-pass type I membrane protein
Swiss Prot P18084
克隆类型 Polyclonal Antibody
背景资料 Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM.