Anti-OPA1 Polyclonal Antibody
品牌:solarbio | 货号:K006076P
英文名称 |
Anti-OPA1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BERHS;MGM1;MTDPS14;NPG;NTG;largeG |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
112kDa |
Gene ID |
4976 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human OPA1 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human OPA1 |
Subcellular Locations |
Mitochondrion inner membrane Mitochondrion intermembrane space Single-pass membrane protein |
Swiss Prot |
O60313 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |