Anti-POR Polyclonal Antibody
品牌:solarbio | 货号:K005679P
英文名称 |
Anti-POR Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CPR;CYPOR;P450R |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
77kDa |
Gene ID |
5447 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human POR |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human POR |
Subcellular Locations |
Endoplasmic reticulum membrane Peripheral membrane protein |
Swiss Prot |
P16435 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. |