Anti-TNNI2 Polyclonal Antibody
品牌：solarbio | 货号：K005566P
| 英文名称 | Anti-TNNI2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AMCD2B;DA2B;FSSV;fsTnI |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 21kDa |
| Gene ID | 7136 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human TNNI2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human TNNI2 |
| Subcellular Locations | Cytoskeleton Cytosol Nucleus |
| Swiss Prot | P48788 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. |